First Report of AIDS

First Report of AIDS

On June 5, 1981, MMWR published a report of five cases of Pneumocystiscarinii pneumonia(PCP)amongpreviouslyhealthyyoungmeninLos Angeles (1 ). All of the men were described as “homosexuals”; two had died. Local clinicians and the Epidemic Intelligence Service (EIS) Officer stationed at the Los Angeles County Department of Public Health, prepared the report and submitted it forMMWR publicationinearlyMay1981.Beforepublication,MMWR editorialstaff sent the submission to CDC experts in parasitic and sexually transmitted diseases. The editorial note that accompanied the published report stated that the case histo- ries suggested a “cellular-immune dysfunction related to a common exposure” and a “disease acquired through sexual contact.” The report prompted additional case reports from New York City, San Francisco, and other cities. At about the same time, CDC’s investigation drug unit, the sole distributor of pentamidine, the therapy for PCP, began to receive requests for the drug from physicians also to treat young men. In June 1981, CDC developed an investigative team to identify risk factors and to develop a case definition for national surveillance. Within 18 months, epidemiolo- gistsconductedstudiesandpreparedMMWR reportsthatidentifiedallofthemajor risks factors for acquired immnodeficiency syndrome (AIDS). In March 1983, CDC issued recommendations for prevention of sexual, drug-related, and occupational transmission based on these early epidemiologic studies and before the cause of the new, unexplained illness was known.

MMWR has published more than 400 reports about human immunodeficiency virus (HIV) and AIDS and remains a primary source of information about the epide- miology, surveillance, prevention, care, and treatment of HIV and AIDS. This anniver- sary issue provides new reports on the epidemiologic features and impact of HIV/ AIDS on communities in the United States and in other countries. A compilation of notableMMWR reportsonHIVandAIDSisavailableathttp://www.cdc.gov/mmwr/ hiv_aids20.html. A video that includes interviews with participants in these first AIDS investigations and reports and a video summary of each report in this issue is avail- able at http://www.cdc.gov/mmwr. 


Reference
1. CDC. Pneumocystis pneumonia — Los Angeles. MMWR 1981;30:250–2.